Chirality ProgramMediaEnantioselective AnalysisDirhodium CatalysisLipase CatalysisPolymer MonolithSilica MonolithMiniaturized systemsDr Ashraf GhanemPublicationsCollaborationsFundOpen positionsMSc/PhD/Post. docNewsGroup photosPhoto AlbumsRACI/ACTCrystal Growing CompetitionCommunity engagement

Synthesis of hybrid silica monolith with definte morphology and pore size



Monolithic silica columns have shown to have superior performance as compared to particle packed columns. They afford fast analysis by bypassing the limitations imposed by pressure via the through-pores, which allow higher flow rates than particulate columns at reasonable column backpressures. Analyte capacity is usually provided within the monolithic structure by the smaller mesopores.
Our interests lie in the preparation of achiral and chiral hybrid micro-sized silica monoliths with superior performance for multi-mode application in achiral and chiral micro-HPLC.
1.   A. Ghanem and T. Ikegami “Recent advances in silica monolith” J. Sep. Sci. 2011, 34, 1945–1957. 
2.   A. Ghanem, T. Ikegami, N. Tanaka “New Silica Monolith Bonded Chiral (R)-γ Butyrolactone for Enantioselective Micro High-Performance Liquid Chromatography” Chirality 2011, 23 (10) 887-890.

Copyright 2013, A. Ghanem